THURSDAY, June 23, 2016 (HealthDay Information) — A sure sort of medical scan can be utilized to assist spare some Hodgkin lymphoma sufferers from the extreme uncomfortable side effects of chemotherapy, a brand new research suggests.

Researchers discovered that PET imaging can determine sufferers whose Hodgkin lymphoma will probably reply higher to remedy, and subsequently require much less intensive chemotherapy.

“The excellent news is that almost all of individuals recognized with Hodgkin lymphoma might be cured — on this trial greater than ninety five % of sufferers are alive after three years. However we fear concerning the lengthy-time period unwanted side effects from the remedies we use,” research chief Peter Johnson, a professor of medical oncology on the College of Southampton in England, stated in a college information launch.

“As we have completed on this trial, personalizing remedy based mostly on how nicely it really works is a serious improvement for sufferers with Hodgkin lymphoma, and units a brand new normal of care,” he famous.

PET scans got to greater than 1,200 sufferers with superior Hodgkin lymphoma who had undergone two cycles of ordinary chemotherapy. These with a transparent scan continued chemotherapy with out the drug bleomycin. Those that did not have a transparent scan — suggesting a extra resistant type of the blood most cancers — continued chemotherapy with bleomycin.

Bleomycin has been used to deal with Hodgkin lymphoma for 30 years, researchers stated. However, the drug can result in scarring of the lungs that may trigger critical respiration issues.

Sufferers with clear PET scans who stopped receiving bleomycin had the identical survival fee as those that continued receiving the drug, based on the research.

“Understanding which sufferers have a harder-to-deal with type of the illness means we will choose those that want stronger chemotherapy, whereas sparing everybody else the extreme unwanted side effects reminiscent of infertility,” Johnson stated.

“This strategy, together with a discount within the want for radiotherapy, ought to considerably scale back injury to wholesome tissues and the danger of second cancers brought on by remedies,” he added.

The research was revealed within the June 22 problem of the New England Journal of Drugs.

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